CAS No. 638-23-3
Batch:
Purity:100.00
Chemical Structure
Check the
Carbocisteine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 638-23-3 | |
|---|---|---|
| Molecular Formula |
C5H9NO4S |
|
| Molecular Weight (MW) | 179.19 | |
| SMILES | C(C(C(=O)O)N)SCC(=O)O |
Biological Activity
Carbocisteine is a mucolytic agent and antioxidant that modulates mucus secretion and suppresses airway inflammation. It reduces the expression of intercellular adhesion molecule-1 (ICAM-1) and inhibits NF-kB signaling pathways, leading to a decrease in the production of pro-inflammatory cytokines such as IL-6 and IL-8 in human airway epithelial cells. Through these mechanisms, carbocisteine decreases sputum viscosity and restores normal mucociliary function. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| 5%TFA | 6.02 mg/mL |
| DMSO |
0.01 mg/mL
(0.05 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.