CAS No. 97-67-6
Batch:
Purity:99.06
Chemical Structure
Check the
(S)-2-Hydroxysuccinic acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 97-67-6 | |
|---|---|---|
| Molecular Formula |
C4H6O5 |
|
| Molecular Weight (MW) | 134.09 | |
| SMILES | C(C(C(=O)O)O)C(=O)O |
(S)-2-Hydroxysuccinic acid (L-Malic acid) is a naturally occurring dicarboxylic acid and a key metabolic intermediate in the tricarboxylic acid (TCA) cycle. It is reversibly oxidized to oxaloacetate by malate dehydrogenase with the concomitant reduction of NAD+ to NADH, thereby fueling oxidative phosphorylation and ATP production. Furthermore, L-malate participates in the malate-aspartate shuttle to transport reducing equivalents across the inner mitochondrial membrane, supporting cellular energy homeostasis. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
27 mg/mL
(201.35 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- (S)-2-Hydroxysuccinic acid Solubility in DMSO
- (S)-2-Hydroxysuccinic acid Stock Solution
- (S)-2-Hydroxysuccinic acid Storage
- (S)-2-Hydroxysuccinic acid Stability
- (S)-2-Hydroxysuccinic acid Molecular Weight
- (S)-2-Hydroxysuccinic acid SMILES
- (S)-2-Hydroxysuccinic acid Chemical Structure (2D and 3D)
- (S)-2-Hydroxysuccinic acid SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.