CAS No. 52248-03-0
Batch:
Purity:99.00
Chemical Structure
Check the
S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 52248-03-0 | |
|---|---|---|
| Molecular Formula |
C15H23N6O5S.C7H7O3S |
|
| Molecular Weight (MW) | 570.64 |
S-(5'-Adenosyl)-L-methionine (AdoMet) is an essential biological methyl donor and cofactor for enzyme-catalyzed transmethylation reactions, including those mediated by catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMTs). By transferring methyl groups to nucleic acids, proteins, and lipids, AdoMet regulates gene expression, epigenetic modifications, and cellular metabolic pathways, playing a key role in protecting against oxidative stress and modulating anti-apoptotic cellular responses. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(175.24 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt Solubility in DMSO
- S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt Stock Solution
- S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt Storage
- S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt Stability
- S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt Molecular Weight
- S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt Chemical Structure (2D and 3D)
- S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.