CAS No. 11103-72-3

Ruthenium Red Chemical Structure
Chemical Structure
Check the Ruthenium Red product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name azane;bis(oxygen(2-));bis(ruthenium(3+));ruthenium(4+);hexachloride
CAS Number 11103-72-3
Molecular Formula
Molecular Weight (MW) 786.35
InChIKey GOOXRYWLNNXLFL-UHFFFAOYSA-H

Biological Activity

Ruthenium Red is a polycationic inorganic dye and ion channel inhibitor that blocks L-type calcium currents (ICa) and the mitochondrial calcium uniporter (MCU) complex [1][2]. By inhibiting calcium influx through voltage-gated L-type calcium channels and mitochondrial membrane transporters, it attenuates intracellular calcium overload, modulates calcium-dependent signaling pathways, and prevents mitochondrial calcium accumulation and subsequent apoptosis.[1][2]

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Reference

[1] Malécot CO, et al. Br J Pharmacol. 1998;124(3):465-472.

[2] Broekemeier KM, et al. Mol Cell Biochem. 1994;139(1):33-40.

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Note: Technical data last updated: Sep 1, 2026.