CAS No. 1449566-36-2

Batch: Purity:99.39
RS 09 Chemical Structure RS 09 Chemical Structure
Chemical Structure
Check the RS 09 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 1449566-36-2
Molecular Formula

C31H49N9O9

Molecular Weight (MW) 691.78

Ordering Information

Biological Activity

RS 09 is a synthetic peptide mimic of lipopolysaccharide (LPS) that acts as an agonist of Toll-like receptor 4 (TLR4). Upon binding, it activates TLR4 signaling pathways to induce NF-κB activation and downstream inflammatory cytokine release, thereby enhancing immune responses. Furthermore, RS 09 exhibits adjuvant properties in vivo by promoting antigen-specific antibody production and boosting humoral immunity. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (144.55 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 100 mg/mL
Water 25 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.