CAS No. 25875-50-7

Batch: Purity:98
Check CoA
Robenidine Hydrochloride Chemical Structure
Chemical Structure
Check the Robenidine Hydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 1,2-bis[(E)-(4-chlorophenyl)methylideneamino]guanidine;hydrochloride
CAS Number 25875-50-7
Molecular Formula

C15 H13Cl2N5.HCl
Molecular Weight (MW) 370.66
SMILES C1=CC(=CC=C1C=NNC(=NN=CC2=CC=C(C=C2)Cl)N)Cl.Cl
InChIKey LTWIBTYLSRDGHP-HCURTGQUSA-N

Biological Activity

Robenidine Hydrochloride is an anticoccidial agent primarily used in poultry that also displays broad-spectrum antibacterial activity against Gram-positive pathogens. It targets microbial energy metabolism and disrupts cell membrane integrity, resulting in the dissipation of membrane potential and inhibition of ATP synthesis. These actions lead to decreased parasite viability and bacterial cell death, rendering it effective in controlling coccidiosis and bacterial infections.

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 74 mg/mL (199.64 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Jump to

Note: Technical data last updated: Sep 1, 2026.