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RMC-7977 SDS | MSDS

1.PRODUCT AND COMPANY IDENTIFICATION

Product identifier

  • Product Name: RMC-7977
  • Catalog Number: E1858
  • CAS Number: 2765082-12-8
  • IUPAC Name: 3-Oxabicyclo[3.1.0]hexane-6-carboxamide, N -[(2R ,14S ,18S )-2-[5-(4- cyclopropyl-1-piperazinyl)-2-[(1S )-1-methoxyethyl]-3-pyridinyl]-1- ethyl-18,19,20,21-tetrahydro-25,25-dimethyl-15,22-dioxo-17H -5,3- ([4,2]-endo -thiazolopropano[1,3]-endo -pyridazinomethanox ypropano)-1H -indol-14-yl]-, (1α,5α,6α)

Relevant identified uses and uses advised against

  • Identified uses: For research and development use only; laboratory chemicals; manufacture of substances.
  • Uses advised against: Not for pharmaceutical, household, or other unapproved uses.

Details of the supplier

  • Company : Selleck Chemicals
  • TollFree : +1 877 796-6397
  • Tel : +1 832 582-8158
  • Fax : +1 832 582-8590

Emergency telephone number

  • Emergency phone #: +1 832 582-8158

2. HAZARD IDENTIFICATION

2.1 Classification of the substance or mixture No specific data provided for this section.

2.2 GHS label elements, including precautionary statements

  • Pictogram(s): Unknown.
  • Signal word: N/A.
  • Hazard statement(s): N/A.
  • Precautionary statement(s):
    • Prevention: N/A.
    • Response: N/A.
    • Storage: N/A.
    • Disposal: N/A.

2.3 Other hazards which do not result in classification No specific data provided for this section.

3. COMPOSITION/INFORMATION ON INGREDIENTS

3.1 Substances

  • Chemical name: 3-Oxabicyclo[3.1.0]hexane-6-carboxamide, N -[(2R ,14S ,18S )-2-[5-(4- cyclopropyl-1-piperazinyl)-2-[(1S )-1-methoxyethyl]-3-pyridinyl]-1- ethyl-18,19,20,21-tetrahydro-25,25-dimethyl-15,22-dioxo-17H -5,3- ([4,2]-endo -thiazolopropano[1,3]-endo -pyridazinomethanox ypropano)-1H -indol-14-yl]-, (1α,5α,6α)
  • Common names and synonyms: RMC-7977
  • CAS number: 2765082-12-8
  • EC number: N/A.

4. FIRST-AID MEASURES

4.1 Description of necessary first-aid measures

  • General advice: N/A.
  • If inhaled: Move the individual to fresh air. If breathing is labored, administer oxygen. If breathing has ceased, perform artificial respiration and seek immediate medical attention. Do not use mouth-to-mouth resuscitation if the substance was inhaled or ingested.
  • Following skin contact: Immediately remove all contaminated clothing. Wash the affected area with soap and a large volume of water. Consult a physician.
  • Following eye contact: Flush eyes with pure water for a minimum of 15 minutes. Consult a physician.
  • Following ingestion: Rinse the mouth with water. Do not induce vomiting. Never administer anything by mouth to an unconscious person. Contact a physician or Poison Control Center immediately.

4.2 Most important symptoms/effects, acute and delayed No specific data provided for this section.

4.3 Indication of immediate medical attention and special treatment needed, if necessary No specific data provided for this section.

5. FIRE-FIGHTING MEASURES

5.1 Extinguishing media Suitable extinguishing media include dry chemical, carbon dioxide, or alcohol-resistant foam.

5.2 Specific hazards arising from the chemical No specific data provided for this section.

5.3 Special protective actions for fire-fighters Firefighters should wear self-contained breathing apparatus (SCBA) if necessary.

6. ACCIDENTAL RELEASE MEASURES

6.1 Personal precautions, protective equipment and emergency procedures Avoid the formation of powder. Avoid breathing any mist, gas, or vapors. Ensure adequate ventilation and use required personal protective equipment. Wear chemical-impermeable gloves and avoid contact with skin and eyes. Remove all potential sources of ignition and evacuate personnel to safe areas, keeping people upwind of the spill.

6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not allow the chemical to enter the drainage system. Avoid discharge into the environment.

6.3 Methods and materials for containment and cleaning up Collect the material and arrange for disposal in suitable, closed containers. Ensure the use of spark-proof tools and explosion-proof equipment. Remove all ignition sources. Adhered or collected material must be disposed of promptly in compliance with applicable laws and regulations.

7. HANDLING AND STORAGE

7.1 Precautions for safe handling Operate in a well-ventilated area. Wear appropriate protective clothing. Avoid contact with eyes and skin. Prevent the formation of powder and aerosols. Use non-sparking tools and take precautions against fire caused by electrostatic discharge.

7.2 Conditions for safe storage, including any incompatibilities Keep containers tightly closed in a cool, dry, and well-ventilated location. Store away from foodstuffs and incompatible materials. Maintain at low temperatures and protect from moisture.

  • powder: -20°C for 3 years.
  • In solvent: -80°C for 1 year.

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

8.1 Control parameters

  • Occupational Exposure limit values: N/A.
  • Biological limit values: N/A.

8.2 Appropriate engineering controls Ensure adequate ventilation. Handle the material in accordance with high-standard industrial hygiene and safety practices. Establish emergency exits and risk-elimination zones.

8.3 Individual protection measures, such as personal protective equipment (PPE)

  • Eye/face protection: Wear tightly fitting safety goggles with side-shields (conforming to NIOSH (US) or EN 166 (EU)).
  • Skin protection: Wear fire/flame-resistant and impervious protective clothing. Handle with gloves inspected prior to use. Wash and dry hands thoroughly. Gloves must meet the specifications of EU Directive 89/686/EEC and the EN 374 standard.
  • Respiratory protection: Use a full-face respirator if exposure limits are exceeded or if irritation/symptoms occur.
  • Thermal hazards: N/A.

9. PHYSICAL AND CHEMICAL PROPERTIES

  • Physical state: powder
  • Color: N/A.
  • Odour: N/A.
  • Melting point/freezing point: N/A.
  • Boiling point or initial boiling point and boiling range: N/A.
  • Flammability: N/A.
  • Lower and upper explosion limit/flammability limit: N/A.
  • Flash point: N/A.
  • Auto-ignition temperature: N/A.
  • Decomposition temperature: N/A.
  • pH: N/A.
  • Kinematic viscosity: N/A.
  • Solubility: DMSO: 120 mg/mL (138.71 mM); sonication is recommended. (Solubility < 1 mg/ml indicates the product is slightly soluble or insoluble).
  • N-octanol-water partition coefficient: N/A.
  • Vapour pressure: N/A.
  • Density and/or relative density: N/A.
  • Relative vapour density: N/A.
  • Particle characteristics: N/A.

10. STABILITY AND REACTIVITY

10.1 Reactivity No specific data provided for this section.

10.2 Chemical stability No specific data provided for this section.

10.3 Possibility of hazardous reactions No specific data provided for this section.

10.4 Conditions to avoid No specific data provided for this section.

10.5 Incompatible materials No specific data provided for this section.

10.6 Hazardous decomposition products No specific data provided for this section.

11. TOXICOLOGICAL INFORMATION

  • Acute toxicity: N/A for oral, inhalation, or dermal routes.
  • Skin corrosion/irritation: N/A.
  • Serious eye damage/irritation: N/A.
  • Respiratory or skin sensitization: N/A.
  • Germ cell mutagenicity: N/A.
  • Carcinogenicity: N/A.
  • Reproductive toxicity: N/A.
  • STOT-single exposure: N/A.
  • STOT-repeated exposure: N/A.
  • Aspiration hazard: N/A.

12. ECOLOGICAL INFORMATION

12.1 Toxicity N/A regarding toxicity to fish, daphnia, aquatic invertebrates, algae, or microorganisms.

12.2 Persistence and degradability No specific data provided for this section.

12.3 Bioaccumulative potential No specific data provided for this section.

12.4 Mobility in soil No specific data provided for this section.

12.5 Other adverse effects No specific data provided for this section.

13. DISPOSAL CONSIDERATIONS

13.1 Disposal methods

  • Product: The material should be disposed of at a licensed chemical destruction plant or via controlled incineration equipped with flue gas scrubbing. Do not contaminate water, food, or feed during storage or disposal. Do not discharge into sewer systems.
  • Contaminated packaging: Containers should be triple-rinsed and offered for recycling or reconditioning. Alternatively, packaging may be punctured to render it unusable and disposed of in a sanitary landfill. Controlled incineration is an option for combustible packaging materials.

14. TRANSPORT INFORMATION

  • 14.1 UN Number: N/A.
  • 14.2 UN Proper Shipping Name: N/A.
  • 14.3 Transport hazard class(es): N/A.
  • 14.4 Packing group, if applicable: N/A.
  • 14.5 Environmental hazards: N/A.
  • 14.6 Special precautions for user: N/A.
  • 14.7 Transport in bulk according to IMO instruments: N/A.

15. REGULATORY INFORMATION

15.1 Safety, health and environmental regulations specific for the product in question

  • European Inventory of Existing Commercial Chemical Substances (EINECS): Not Listed.
  • EC Inventory: Not Listed.
  • United States Toxic Substances Control Act (TSCA) Inventory: Not Listed.
  • China Catalog of Hazardous chemicals 2015: Not Listed.
  • New Zealand Inventory of Chemicals (NZIoC): Not Listed.
  • Philippines Inventory of Chemicals and Chemical Substances (PICCS): Not Listed.
  • Vietnam National Chemical Inventory: Not Listed.
  • Chinese Chemical Inventory of Existing Chemical Substances (China IECSC): Not Listed.
  • Korea Existing Chemicals List (KECL): Not Listed.

16. OTHER INFORMATION

Revision Date: 2026/05/28 Further Information: The information provided is believed to be correct but is not exhaustive and should be used only as a guideline based on current knowledge. It does not represent a guarantee of the properties of the product. Selleck Chemicals Corporation and its Affiliates shall not be held liable for any damage resulting from handling or contact with the product.

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