SMILES:
Cl.CN(C)C(=O)C1=CC2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2[N]1C5CCCC5
Chemical Structure
Check the
Ribociclib hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 7-cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-yl-2-pyridinyl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide;hydrochloride | |
|---|---|---|
| CAS Number | 1211443-80-9 | |
| Molecular Formula |
C23H31ClN8O |
|
| Molecular Weight (MW) | 471 | |
| SMILES | Cl.CN(C)C(=O)C1=CC2=CN=C(NC3=NC=C(C=C3)N4CCNCC4)N=C2[N]1C5CCCC5 | |
| InChIKey | JZRSIQPIKASMEV-UHFFFAOYSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
94 mg/mL
(199.57 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 94 mg/mL |
| Ethanol | 94 mg/mL |
| DMSO |
94 mg/mL
(199.57 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 94 mg/mL |
| Ethanol | 94 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Ribociclib hydrochloride Clinical Trials
- Ribociclib hydrochloride Solubility in DMSO
- Ribociclib hydrochloride Stock Solution
- Ribociclib hydrochloride Storage
- Ribociclib hydrochloride Stability
- Ribociclib hydrochloride Molecular Weight
- Ribociclib hydrochloride CAS Number
- Ribociclib hydrochloride Chemical Structure (2D and 3D)
- Ribociclib hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.