CAS No. 17306-46-6
Batch:
Purity:99.29
Chemical Structure
Check the
Rhoifolin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 17306-46-6 | |
|---|---|---|
| Molecular Formula |
C27H30O14 |
|
| Molecular Weight (MW) | 578.52 | |
| SMILES | CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC=C(C=C5)O)O)CO)O)O)O)O)O |
Rhoifolin is a naturally occurring flavone glycoside of apigenin that exhibits diverse biological activities, including antioxidant, anti-inflammatory, antimicrobial, hepatoprotective, and anticancer effects. It modulates key cellular signaling pathways such as NF-kB and MAPK to suppress downstream pro-inflammatory cytokine production and attenuate oxidative stress. Furthermore, rhoifolin inhibits cell proliferation and induces apoptosis, highlighting its potential bioactivity in preclinical model research. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
10 mg/mL
(17.28 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
100 mg/mL
(172.85 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(172.85 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.