CAS No. 989-38-8
Batch:
Purity:98
Chemical Structure
Check the
Rhodamine 6G
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | [9-(2-ethoxycarbonylphenyl)-6-(ethylamino)-2,7-dimethylxanthen-3-ylidene]-ethylazanium chloride | |
|---|---|---|
| CAS Number | 989-38-8 | |
| Molecular Formula |
C28H31ClN2O3 |
|
| Molecular Weight (MW) | 479.01 | |
| SMILES | [Cl-].CCNC1=CC2=C(C=C1C)C(=C3C=C(C)C(C=C3O2)=[NH+]CC)C4=CC=CC=C4C(=O)OCC | |
| InChIKey | VYXSBFYARXAAKO-UHFFFAOYSA-N |
Rhodamine 6G is a cell-permeable lipophilic cationic fluorescent dye and inhibitor of mitochondrial oxidative phosphorylation. Upon selective uptake into mitochondria driven by membrane potential, Rhodamine 6G disrupts mitochondrial membrane integrity, reduces intact mitochondrial counts, and impairs ATP synthesis. Consequently, this leads to the inhibition of cellular respiration, suppression of metabolic activity, and induction of cytotoxic responses in targeted cells. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
96 mg/mL
(200.41 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 96 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.