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Resatorvid (TAK-242) SDS | MSDS

1.PRODUCT AND COMPANY IDENTIFICATION

Product identifier

  • Product Name: Resatorvid (TAK-242)
  • Catalog Number: S7455
  • CAS Number: 243984-11-4
  • IUPAC Name: 1-Cyclohexene-1-carboxylic acid, 6-[[(2-chloro-4-fluorophenyl)amino]sulfonyl]-, ethyl ester, (6R)-

Relevant identified uses and uses advised against

  • Identified uses: For research and development use only; laboratory chemicals; manufacture of substances.
  • Uses advised against: Not for pharmaceutical, household, or other unapproved uses.

Details of the supplier

  • Company : Selleck Chemicals
  • TollFree : +1 877 796-6397
  • Tel : +1 832 582-8158
  • Fax : +1 832 582-8590

Emergency telephone number

  • Emergency phone #: +1 832 582-8158

2. HAZARDS IDENTIFICATION

GHS Classification:
According to the OSHA Hazard Communication Standard (29 CFR 1910.1200), the product as supplied is not classified as a hazardous substance or mixture.

GHS Label Elements:
The product does not require hazard pictograms, signal words, hazard statements, or precautionary statements.

Other Hazards:
None known.

3. COMPOSITION/INFORMATION ON INGREDIENTS

Substance/Mixture: Substance
Chemical Name: 1-Cyclohexene-1-carboxylic acid, 6-[[(2-chloro-4-fluorophenyl)amino]sulfonyl]-, ethyl ester, (6R)-
CAS-No.: 243984-11-4
Components: No hazardous ingredients are present in this substance.

4. FIRST AID MEASURES

Inhalation: If inhaled, move the person to fresh air.
Skin Contact: Immediately remove all contaminated clothing. Rinse the affected skin area with water or shower.
Eye Contact: Rinse eyes thoroughly with plenty of water. Remove contact lenses if present.
Ingestion: If swallowed, provide the victim with a maximum of two glasses of water. Consult a physician if the individual feels unwell.
Most Important Symptoms and Effects: The most important known symptoms and effects are described in the labeling (see Section 2) and/or Section 11.
Protection of First-Aiders: Refer to Section 8 for personal protective equipment.
Notes to Physician: N/A.

5. FIREFIGHTING MEASURES

Extinguishing Media: Use water, foam, carbon dioxide (CO2), or dry powder.
Unsuitable Extinguishing Media: No limitations of extinguishing agents are specified for this substance.
Specific Hazards: The product is combustible. Fire may lead to the evolution of hazardous gases or vapors, including hydrogen fluoride, hydrogen chloride gas, nitrogen oxides (NOx), and sulfur oxides.
Hazardous Combustion Products: Carbon oxides, nitrogen oxides (NOx), sulfur oxides, hydrogen chloride gas, and hydrogen fluoride.
Extinguishing Methods: Use water spray jet to suppress gases, vapors, or mists. Prevent firefighting water from entering surface water or groundwater systems.
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus in the event of a fire.

6. ACCIDENTAL RELEASE MEASURES

Personal Precautions and Protective Equipment:

  • For non-emergency personnel: Avoid inhalation of dusts. Evacuate the danger area, observe emergency procedures, and consult an expert.
  • For emergency responders: Use personal protection as recommended in Section 8.

Environmental Precautions: Do not allow the product to enter drains.
Methods for Containment and Cleaning Up: Cover drains. Collect, bind, and pump off spills. Observe material restrictions as noted in Sections 7 and 10. Take up the material dry and dispose of it properly. Clean the affected area and avoid the generation of dusts.

7. HANDLING AND STORAGE

Handling: Follow precautions outlined in Section 2.2.
Storage Conditions: Keep the container tightly closed and in a dry location.
Storage Class: 11 (Combustible Solids).
Storage Temperature: Refer to the product label for the recommended storage temperature.
Storage Stability: Recommended storage temperature is specified on the product label.

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Exposure Guidelines: Contains no substances with occupational exposure limit values.
Engineering Measures: No specific data provided for this section.
Personal Protective Equipment:

  • Respiratory Protection: Required when dusts are generated. Recommended filter type: P1 (based on DIN EN 143, DIN 14387).
  • Hand Protection: Use nitrile rubber gloves. Full contact and splash contact: Minimum layer thickness 0.11 mm, break-through time 480 min (e.g., KCL 741 Dermatril-L).
  • Eye Protection: Use safety glasses tested and approved under government standards such as NIOSH (US) or EN 166 (EU).
  • Hygiene Measures: Change contaminated clothing and wash hands after handling the substance.

9. PHYSICAL AND CHEMICAL PROPERTIES

Appearance: powder
Color: yellow to white
Odor: N/A
Odor Threshold: N/A
pH: N/A
Melting Point: 129 - 131 °F / 54 - 55 °C
Boiling Point: N/A
Flash Point: Not applicable
Evaporation Rate: N/A
Flammability (solid, gas): N/A
Upper/Lower Explosion Limit: N/A
Vapor Pressure: N/A
Relative Vapor Density: N/A
Relative Density: N/A
Density: N/A
Water Solubility: slightly soluble
Partition Coefficient (n-octanol/water): log Pow: ca. 3.0 (calculated); bioaccumulation is not expected.
Autoignition Temperature: N/A
Decomposition Temperature: N/A
Viscosity: N/A
Explosive Properties: Not classified as explosive.
Oxidizing Properties: none
Molecular Weight: 361.82 g/mol

10. STABILITY AND REACTIVITY

Reactivity: Flammable organic substances in fine distribution may have dust explosion potential when whirled up.
Chemical Stability: The product is chemically stable under standard ambient conditions (room temperature).
Possibility of Hazardous Reactions: N/A.
Conditions to Avoid: No information available.
Incompatible Materials: Strong oxidizing agents.
Hazardous Decomposition Products: In the event of fire, see Section 5.

11. TOXICOLOGICAL INFORMATION

Acute Toxicity: N/A for oral, inhalation, or dermal routes.
Skin Corrosion/Irritation: N/A.
Serious Eye Damage/Irritation: N/A.
Respiratory or Skin Sensitization: N/A.
Germ Cell Mutagenicity: N/A.
Carcinogenicity:

  • IARC: No component present at levels >= 0.1% is identified as a probable, possible, or confirmed human carcinogen.
  • NTP: No component present at levels >= 0.1% is identified as a known or anticipated carcinogen.
  • OSHA: No component present at levels >= 0.1% is on OSHA’s list of regulated carcinogens.
    Reproductive Toxicity: N/A.
    STOT - Single Exposure: N/A.
    STOT - Repeated Exposure: N/A.
    Aspiration Hazard: N/A.
    Additional Information: N/A.

12. ECOLOGICAL INFORMATION

Ecotoxicity: N/A.
Persistence and Degradability: N/A.
Bioaccumulative Potential: N/A.
Mobility in Soil: N/A.
Other Adverse Effects: This product does not contain and was not manufactured with Class I or Class II ODS as defined by the U.S. Clean Air Act Section 602 (40 CFR 82, Subpt. A, App. A + B).

13. DISPOSAL CONSIDERATIONS

Waste Treatment Methods: Waste material must be disposed of in accordance with national and local regulations. Leave chemicals in original containers and do not mix with other waste. Handle uncleaned containers in the same manner as the product itself.

14. TRANSPORT INFORMATION

DOT (49 CFR): Not regulated as a dangerous good.
IATA: Not regulated as a dangerous good.
IMDG: Not regulated as a dangerous good.
Transport in Bulk: Not applicable for the product as supplied.
Special Precautions: Not classified as dangerous in the meaning of transport regulations. Poison Inhalation Hazard: No.

15. REGULATORY INFORMATION

CERCLA Reportable Quantity
This material does not contain any components with a CERCLA RQ.

SARA 304 Extremely Hazardous Substances Reportable Quantity
This material does not contain any components with a section 304 EHS RQ.

SARA 302 Extremely Hazardous Substances Threshold Planning Quantity
This material does not contain any components with a section 302 EHS TPQ.

SARA 313
This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

Clean Air Act
This product neither contains, nor was manufactured with a Class I or Class II ODS as defined by the U.S. Clean Air Act Section 602 (40 CFR 82, Subpt. A, App.A + B).
This product does not contain any hazardous air pollutants (HAP), as defined by the U.S. Clean Air Act Section 112 (40 CFR 61).
This product does not contain any chemicals listed under the U.S. Clean Air Act Section 112(r) for Accidental Release Prevention (40 CFR 68.130, Subpart F).
This product does not contain any chemicals listed under the U.S. Clean Air Act Section 111 SOCMI Intermediate or Final VOC's (40 CFR 60.489).

Clean Water Act
This product does not contain any Hazardous Substances listed under the U.S. CleanWater Act, Section 311, Table 116.4A.
This product does not contain any Hazardous Chemicals listed under the U.S. CleanWater Act, Section 311, Table 117.3.
This product does not contain any toxic pollutants listed under the U.S. Clean Water Act Section 307
This product does not contain any priority pollutants related to the U.S. Clean Water Act

US State Regulations
Massachusetts Right To Know
No components are subject to the Massachusetts Right to Know Act.
Maine Chemicals of High Concern
Product does not contain any listed chemicals
Vermont Chemicals of High Concern
Product does not contain any listed chemicals
Washington Chemicals of High Concern
Product does not contain any listed chemicals

The components of this product are reported in the following inventories:
TSCA : Product contains substance(s) not listed on TSCA inventory.

TSCA list
No substances are subject to a Significant New Use Rule.
No substances are subject to TSCA 12(b) export notification requirements.

16. OTHER INFORMATION

Revision Date: 2026/07/16
Further Information: The information provided is believed to be correct but is not exhaustive and should be used only as a guideline based on current knowledge. It does not represent a guarantee of the properties of the product. Selleck Chemicals Corporation and its Affiliates shall not be held liable for any damage resulting from handling or contact with the product.

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