CAS No. 81720-08-3
Batch:
Purity:97.66
Chemical Structure
Check the
Rehmannioside D (Rhmannioside D)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 81720-08-3 | |
|---|---|---|
| Molecular Formula |
C27H42O20 |
|
| Molecular Weight (MW) | 686.61 |
Rehmannioside D is a natural iridoid glycoside derived from Rehmannia glutinosa that acts by directly interacting with c-Jun and suppressing MAPK and NF-kB signaling pathways. Disruption of c-Jun heterodimerization with c-Fos dismantles the AP-1 complex and suppresses NFATc1 expression. These molecular events trigger intrinsic apoptosis and inhibit RANKL-induced osteoclastogenesis and osteoclast function, demonstrating potential protective activity against bone loss. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 100 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Rehmannioside D (Rhmannioside D) Solubility in DMSO
- Rehmannioside D (Rhmannioside D) Stock Solution
- Rehmannioside D (Rhmannioside D) Storage
- Rehmannioside D (Rhmannioside D) Stability
- Rehmannioside D (Rhmannioside D) Molecular Weight
- Rehmannioside D (Rhmannioside D) Chemical Structure (2D and 3D)
- Rehmannioside D (Rhmannioside D) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.