CAS No. 161735-79-1

Batch: Purity:99.85
Rasagiline Mesylate Chemical Structure
Chemical Structure
Check the Rasagiline Mesylate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name methanesulfonic acid;(1R)-N-prop-2-ynyl-2,3-dihydro-1H-inden-1-amine
CAS Number 161735-79-1
Molecular Formula

C12H13N.CH4O3S

Molecular Weight (MW) 267.34
SMILES CS(=O)(=O)O.C#CCNC1CCC2=CC=CC=C12
InChIKey JDBJJCWRXSVHOQ-UTONKHPSSA-N

Ordering Information

Biological Activity

Rasagiline Mesylate is a potent and selective irreversible monoamine oxidase B (MAO-B) inhibitor. By inhibiting MAO-B activity, it blocks the oxidative deamination of dopamine, leading to elevated dopamine concentrations in the central nervous system. Downstream, rasagiline protects against dopaminergic neuronal apoptosis and attenuates oxidative stress-induced cell damage, thereby preserving neurochemical pathways critical for motor regulation. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 53 mg/mL (198.24 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 53 mg/mL
Ethanol 53 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.