CAS No. 1176-09-6
Chemical Structure
Check the
Raptinal
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 9-(9-formylfluoren-9-yl)fluorene-9-carbaldehyde | |
|---|---|---|
| CAS Number | 1176-09-6 | |
| Molecular Formula |
C28H18O2 |
|
| Molecular Weight (MW) | 386.44 | |
| InChIKey | GLANOOJJBKXTMI-UHFFFAOYSA-N |
Raptinal is a pro-apoptotic compound that promotes mitochondrial cytochrome c release to activate the intrinsic apoptotic pathway. Additionally, Raptinal inhibits caspase-activated Pannexin 1 (PANX1), a transmembrane channel involved in cell death regulation. By triggering mitochondrial cytochrome c release and inhibiting PANX1 channel activity, Raptinal suppresses PANX1-dependent cellular processes, including extracellular ATP release and NLRP3 inflammasome activation, leading to rapid induction of apoptosis.
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Note: Technical data last updated: Sep 1, 2026.