Molecular Weight: 478.94 g/mol

Raf inhibitor 1 Chemical Structure
Chemical Structure
Check the Raf inhibitor 1 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
1 mg 5 mg 10 mg
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 96 mg/mL (200.44 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Chemical Information

IUPAC Name 1-N-(4-chlorophenyl)-6-methyl-5-N-[3-(7H-purin-6-yl)-2-pyridinyl]isoquinoline-1,5-diamine
CAS Number 1093100-40-3
Molecular Formula

C26H19ClN8
Molecular Weight (MW) 478.94
SMILES CC1=C(NC2=NC=CC=C2C3=C4N=C[NH]C4=NC=N3)C5=C(C=C1)C(=NC=C5)NC6=CC=C(Cl)C=C6
InChIKey KKVYYGGCHJGEFJ-UHFFFAOYSA-N

Jump to

Note: Technical data last updated: Sep 1, 2026.