CAS No. 117976-90-6

Batch: Purity:97
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Rabeprazole sodium Chemical Structure
Chemical Structure
Check the Rabeprazole sodium product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name sodium 2-[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methylsulfinyl]benzimidazol-1-ide
CAS Number 117976-90-6
Molecular Formula

C18H20N3O3S.Na
Molecular Weight (MW) 381.42
SMILES CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3[N-]2)OCCCOC.[Na+]
InChIKey KRCQSTCYZUOBHN-UHFFFAOYSA-N

Ordering Information

Biological Activity

Rabeprazole sodium is a proton pump inhibitor that targets gastric H+/K+-ATPase. By inhibiting gastric H+/K+-ATPase in parietal cells, it suppresses the final enzymatic step of gastric acid secretion. This inhibition blocks the transmembrane exchange of hydrogen and potassium ions, leading to reduced luminal acid accumulation and decreased basal and stimulated gastric acid production. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 76 mg/mL (199.25 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.