CAS No. 631-01-6

Batch: Purity:99.83
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Quillaic acid Chemical Structure
Chemical Structure
Check the Quillaic acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 631-01-6
Molecular Formula

C30H46O5
Molecular Weight (MW) 486.68
SMILES CC1(CCC2(C(C1)C3=CCC4C5(CCC(C(C5CCC4(C3(CC2O)C)C)(C)C=O)O)C)C(=O)O)C

Ordering Information

Biological Activity

Quillaic acid is a natural triterpenoid aglycone derived from Quillaja saponaria that possesses potent anti-inflammatory activity. It inhibits inflammatory mediator production and suppresses downstream signaling cascades involved in inflammatory responses, thereby attenuating edema and tissue inflammation in preclinical models. These biological activities highlight its function as a key bioactive metabolite underlying saponin-mediated anti-inflammatory effects.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 97 mg/mL (199.3 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 14 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.