CAS No. 1135695-98-5
Batch:
Purity:99.72
Chemical Structure
Check the
Q-VD-Oph
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (3S)-5-(2,6-difluorophenoxy)-3-[[(2S)-3-methyl-2-(quinoline-2-carbonylamino)butanoyl]amino]-4-oxopentanoic acid | |
|---|---|---|
| CAS Number | 1135695-98-5 | |
| Molecular Formula |
C26H25F2N3O6
|
|
| Molecular Weight (MW) | 513.49 | |
| SMILES | CC(C)C(C(=O)NC(CC(=O)O)C(=O)COC1=C(C=CC=C1F)F)NC(=O)C2=NC3=CC=CC=C3C=C2 | |
| InChIKey | OOBJCYKITXPCNS-REWPJTCUSA-N |
Q-VD-Oph is a cell-permeable pan-caspase inhibitor that targets caspase-1, caspase-3, caspase-8, and caspase-9 with IC50 values ranging from 25 to. By inhibiting caspase cleavage and downstream apoptotic signaling cascades, it prevents programmed cell death across diverse cell types. Additionally, Q-VD-Oph blocks viral-induced cell death and inhibits HIV infection in target cells without exhibiting significant cellular toxicity. [1]
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(194.74 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(194.74 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(194.74 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(194.74 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(194.74 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Q-VD-Oph Mechanism of Action: Pan-caspase Inhibition in Apoptotic Cells Research
- Q-VD-Oph: Selectivity & Specificity
- Q-VD-Oph Working Concentration | Cell Culture | Treatment
- Q-VD-Oph Solubility in DMSO
- Q-VD-Oph Stock Solution
- Q-VD-Oph Storage
- Q-VD-Oph Stability
- Q-VD-Oph Combination Database
- Q-VD-Oph Molecular Weight
- Q-VD-Oph SMILES
- Q-VD-Oph Chemical Structure (2D and 3D)
- Q-VD-Oph Sigma (551476)? Try a better option.
- Q-VD-Oph MedChemExpress (HY-12305)? Try a better option.
- Q-VD-Oph Cayman (15260)? Try a better option.
- Q-VD-Oph Abcam (ab141421)? Try a better option.
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- Q-VD-Oph SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.