CAS No. 3068830-89-4
Chemical Structure
Check the
PZL-A
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 3068830-89-4 | |
|---|---|---|
| Molecular Formula |
C19H17ClN4O2 |
|
| Molecular Weight (MW) | 368.82 |
Biological Activity
PZL-A is an activator of mitochondrial DNA (mtDNA) synthesis that targets polymerase γ (POLγ) to restore activity to mutant enzyme forms. In cellular systems, PZL-A stimulates mtDNA replication, promoting biogenesis of the oxidative phosphorylation complex and enhancing cellular respiration. Consequently, PZL-A represents a promising therapeutic agent for mitigating severe disorders linked to mitochondrial DNA depletion. [1][2]
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Note: Technical data last updated: Sep 1, 2026.