CAS No. 6358-69-6

Pyranine Chemical Structure
Chemical Structure
Check the Pyranine product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 6358-69-6
Molecular Formula

C16H10O10S3.3Na

Molecular Weight (MW) 527.41

Ordering Information

Biological Activity

Pyranine (HPTS) is a cell-impermeant, pH-sensitive fluorescent indicator and hydrophilic optical detecting reagent. It functions as a chemosensor for pH and copper ions (Cu⁺), enabling fluorescence-based optical detection of proton gradients and endosomal acidification. Upon excitation, its pH-dependent fluorescence spectra allow non-invasive quantitative monitoring of intracellular pH changes and endocytic compartment dynamics in biological systems without traversing intact plasma membranes. [1]

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Note: Technical data last updated: Sep 1, 2026.