Molecular Weight: 322.75 g/mol
Chemical Structure
Check the
PS-1145
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
64 mg/mL
(198.29 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 2 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Chemical Information
| IUPAC Name | N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)pyridine-3-carboxamide | |
|---|---|---|
| CAS Number | 431898-65-6 | |
| Molecular Formula |
C17H11ClN4O |
|
| Molecular Weight (MW) | 322.75 | |
| SMILES | C1=CC(=CN=C1)C(=O)NC2=CC(=CC3=C2NC4=C3C=CN=C4)Cl | |
| InChIKey | JZRMBDHPALEPDM-UHFFFAOYSA-N |
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Note: Technical data last updated: Sep 1, 2026.