CAS No. 1370261-97-4
Batch:
Purity:99.69
Chemical Structure
Check the
PRT062607 (P505-15) HCl
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[3-(triazol-2-yl)anilino]pyrimidine-5-carboxamide;hydrochloride | |
|---|---|---|
| CAS Number | 1370261-97-4 | |
| Molecular Formula |
C19H23N9O.HCl |
|
| Molecular Weight (MW) | 429.91 | |
| SMILES | C1CCC(C(C1)N)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)N4N=CC=N4)C(=O)N.Cl | |
| InChIKey | RMNLLPXCNDZJMJ-IDVLALEDSA-N |
PRT062607 HCl is a potent and highly selective inhibitor of spleen tyrosine kinase (Syk). By targeting Syk, this compound effectively blocks downstream B-cell receptor (BCR) and Fc receptor signaling pathways. This inhibition suppresses the activation of downstream signaling cascades, leading to reduced release of inflammatory mediators and attenuated immune cell responses.
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
86 mg/mL
(200.04 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 86 mg/mL |
| Ethanol | Insoluble |
| DMSO |
86 mg/mL
(200.04 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 30 mg/mL |
| Ethanol | Insoluble |
| DMSO |
86 mg/mL
(200.04 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 86 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- PRT062607 (P505-15) HCl Clinical Trials
- PRT062607 (P505-15) HCl Solubility in DMSO
- PRT062607 (P505-15) HCl Stock Solution
- PRT062607 (P505-15) HCl Storage
- PRT062607 (P505-15) HCl Stability
- PRT062607 (P505-15) HCl Molecular Weight
- PRT062607 (P505-15) HCl SMILES
- PRT062607 (P505-15) HCl Chemical Structure (2D and 3D)
- PRT062607 (P505-15) HCl SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.