Molecular Weight: 413.34 g/mol

PRT-060318 2HCl Chemical Structure
Chemical Structure
Check the PRT-060318 2HCl product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 75 mg/mL (181.44 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 75 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Chemical Information

IUPAC Name 2-[(2-aminocyclohexyl)amino]-4-(3-methylanilino)pyrimidine-5-carboxamide
CAS Number 1194961-19-7(freebase)
Molecular Formula

C18H24N6O.2HCl

Molecular Weight (MW) 413.34
SMILES CC1=CC(=CC=C1)NC2=NC(=NC=C2C(=O)N)NC3CCCCC3N
InChIKey NZNTWOVDIXCHHS-UHFFFAOYSA-N

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Note: Technical data last updated: Sep 1, 2026.