CAS No. 102036-29-3
Batch:
Purity:98.81
Chemical Structure
Check the
Protosappanin B
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 102036-29-3 | |
|---|---|---|
| Molecular Formula |
C16H16O6 |
|
| Molecular Weight (MW) | 304.29 | |
| SMILES | C1C2=CC(=C(C=C2C3=C(C=C(C=C3)O)OCC1(CO)O)O)O |
Protosappanin B is a natural dibenzoxocin compound extracted from Lignum Sappan that exhibits potent anti-inflammatory and antioxidant activities. It suppresses inflammatory signaling through modulation of the NF-kB pathway, leading to reduced expression of pro-inflammatory cytokines and attenuated cellular immune responses. Furthermore, Protosappanin B scavenges reactive oxygen species and inhibits proliferation in various cell lines, demonstrating broad protective and anti-proliferative bioactivities.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
61 mg/mL
(200.46 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 61 mg/mL |
| Ethanol | 61 mg/mL |
| DMSO |
61 mg/mL
(200.46 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.