CAS No. 1921-70-6
Batch:
Purity:98.16
Chemical Structure
Check the
Pristane
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 2,6,10,14-tetramethylpentadecane | |
|---|---|---|
| CAS Number | 1921-70-6 | |
| Molecular Formula |
C19H40 |
|
| Molecular Weight (MW) | 268.52 | |
| InChIKey | XOJVVFBFDXDTEG-UHFFFAOYSA-N |
Biological Activity
Pristane (2,6,,-tetramethylpentadecane) is a natural saturated terpenoid alkane and inflammatory adjuvant that triggers Toll-like receptor 7 (TLR7) and type I interferon (IFN-I) signaling through MyD88. This cascade promotes autoantibody production, proinflammatory cytokine secretion, and immune complex deposition, driving downstream phenotypes such as glomerulonephritis, tumorigenesis, and erosive arthritis in animal models of systemic lupus erythematosus. [1][2]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
54 mg/mL
(201.1 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 54 mg/mL |
| Water | Insoluble |
| Ethanol | 100 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.
Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.
Reference
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Note: Technical data last updated: Sep 1, 2026.