CAS No. 2207-75-2

Batch: Purity:99.94
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Potassium Oxonate (Oteracil Potassium) Chemical Structure
Chemical Structure
Check the Potassium Oxonate (Oteracil Potassium) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name potassium 4,6-dioxo-1H-1,3,5-triazine-2-carboxylate
CAS Number 2207-75-2
Molecular Formula

C4H2N3O4.K
Molecular Weight (MW) 194.97
SMILES [K+].[O-]C(=O)C1=NC(=O)NC(=O)N1
InChIKey IAPCTXZQXAVYNG-UHFFFAOYSA-M

Ordering Information

Biological Activity

Potassium oxonate is a selectively competitive uricase inhibitor. By blocking hepatic uricase activity, it prevents the enzymatic oxidation of uric acid to allantoin, leading to systemic urate accumulation. In vivo, administration of potassium oxonate significantly elevates serum uric acid levels to induce acute hyperuricemia in animal models. Consequently, this compound provides a valuable experimental tool for establishing hyperuricemia models to evaluate urate-lowering therapeutic agents and renal pathology. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 7 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.