CAS No. 14941-08-3
Batch:
Purity:99.64
Chemical Structure
Check the
Poncirin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 14941-08-3 | |
|---|---|---|
| Molecular Formula |
C28H34O14 |
|
| Molecular Weight (MW) | 594.56 | |
| SMILES | CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC=C(C=C5)OC)O)CO)O)O)O)O)O |
Poncirin is a natural flavanone glycoside extracted from trifoliate orange with reported anti-inflammatory and antibacterial activities. In macrophage cellular models, poncirin suppresses lipopolysaccharide-induced production of pro-inflammatory mediators, including nitric oxide and prostaglandin E2. Downstream, it inhibits the expression of inducible nitric oxide synthase and cyclooxygenase-2 through the inactivation of the NF-kB signaling pathway, reducing cellular inflammatory phenotypes. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(168.19 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(168.19 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.