CAS No. 13849-91-7
Batch:
Purity:99.46
Chemical Structure
Check the
Pomolic acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (1R,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-1,10-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid | |
|---|---|---|
| CAS Number | 13849-91-7 | |
| Molecular Formula |
C30H48O4 |
|
| Molecular Weight (MW) | 472.70 | |
| SMILES | CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1(C)O)C)C(=O)O | |
| InChIKey | ZZTYPLSBNNGEIS-OPAXANQDSA-N |
Pomolic acid is a naturally occurring pentacyclic triterpene that acts as an inhibitor of cancer cell growth and an inducer of apoptosis. It modulates apoptotic signaling pathways by promoting caspase activation, mitochondrial membrane potential loss, and poly(ADP-ribose) polymerase cleavage, leading to cell cycle arrest and effective inhibition of cell proliferation across various human cancer cell lines.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
10 mg/mL
(21.15 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.