CAS No. 9002-84-0
Batch:
Purity:
Chemical Structure
Check the
Polytetrafluoroethylene
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 9002-84-0 | |
|---|---|---|
| Molecular Formula |
(C2F4)n |
Biological Activity
Polytetrafluoroethylene (PTFE) is a synthetic fluoropolymer biomedical material that regulates cellular adhesion and immune cell responses without classical enzymatic targets. Surface topography of PTFE modulates macrophage adhesion and activation, influencing foreign body giant cell formation and inflammatory cytokine production, including TNF-α and IL-6. Furthermore, expanded PTFE implants elicit host immune activation marked by elevated TNF-α and IL-1α expression, directing local tissue infiltration and cellular responses. [1]
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.