CAS No. 1260-04-4

Batch: Purity:99.92
Polygalic acid Chemical Structure
Chemical Structure
Check the Polygalic acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 1260-04-4
Molecular Formula

C29H44O6

Molecular Weight (MW) 488.66
SMILES CC1(CCC2(CCC3=C(C2C1)CCC4C3(CCC5C4(CC(C(C5(C)C(=O)O)O)O)C)C)C(=O)O)C

Ordering Information

Biological Activity

Polygalic acid, also known as senegenic acid, is a naturally occurring triterpenoid saponin aglycone derived from Polygala species. It exhibits diverse pharmacological activities, serving as an active botanical constituent with expectorant, emetic, and central stimulant effects. These biological properties involve the modulation of cellular stress pathways, membrane interactions, and physiological responses associated with triterpenoid saponin compounds.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 98 mg/mL (200.54 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.