CAS No. 882664-74-6
Batch:
Purity:99.91
Chemical Structure
Check the
Polygalasaponin F
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 882664-74-6 | |
|---|---|---|
| Molecular Formula |
C53H86O23 |
|
| Molecular Weight (MW) | 1091.24 | |
| SMILES | CC1C(C(C(C(O1)OC2C(C(C(OC2OC(=O)C34CCC(CC3C5=CCC6C(C5(CC4)C)(CCC7C6(CC(C(C7(C)CO)OC8C(C(C(C(O8)CO)O)O)O)O)C)C)(C)C)CO)O)O)O)O)OC9C(C(C(CO9)O)O)O |
Polygalasaponin F is a natural triterpenoid saponin isolated from Polygala japonica that acts as a neuroprotective and central nervous system agent. It modulates neuroprotective signaling pathways, enhancing cognitive function while exerting anxiolytic and sedative-hypnotic effects. By mitigating cerebral ischemic damage and modulating central neuronal excitability, polygalasaponin F protects neuronal tissue and supports cognitive recovery in preclinical models.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(91.63 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
100 mg/mL
(91.63 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 5 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.