CAS No. 942425-34-5
Chemical Structure
Check the
PKN1
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 1-ethyl-2-pyridin-4-yl-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-4-one | |
|---|---|---|
| CAS Number | 942425-34-5 | |
| Molecular Formula |
C14H15N3O |
|
| Molecular Weight (MW) | 241.29 | |
| SMILES | CCN1C(C2=CC=NC=C2)=CC3=C1CCNC3=O | |
| InChIKey | RVODROMIHSQWCT-UHFFFAOYSA-N |
Biological Activity
PKN1/2-IN-1 is a cell-permeable kinase inhibitor that selectively targets protein kinase N1 (PKN1) and protein kinase N2 (PKN2). By suppressing PKN signaling, this compound modulates key downstream cellular pathways involved in cytoskeletal organization, cell adhesion, and tumor cell migration. Consequently, it serves as a valuable small-molecule probe for investigating PKN-mediated physiological processes and tumor cell motility. [1]
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Note: Technical data last updated: Sep 1, 2026.