pivalic acid-d9 CAS Number

Pivalic acid-d9 is a deuterium-labeled derivative of pivalic acid (trimethylacetic acid) that serves as a stable isotope internal standard and chemical intermediate for drug synthesis. In biological systems, pivalic acid undergoes metabolic conversion to pivaloyl-coenzyme A, which subsequently reacts with carnitine to form pivaloylcarnitine for renal excretion. This metabolic pathway modulates intracellular acyl-CoA pools and systemic carnitine homeostasis in metabolic and pharmacokinetic research. ^[1]

[1] Brass EP. Pharmacol Rev. 2002;54(4):589-98.