CAS No. 135-87-5
Batch:
Purity:99.89
Chemical Structure
Check the
Piperoxan hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 135-87-5 | |
|---|---|---|
| Molecular Formula |
C14H20ClNO2 |
|
| Molecular Weight (MW) | 269.77 | |
| SMILES | C1CCN(CC1)CC2COC3=CC=CC=C3O2.Cl |
Piperoxan hydrochloride is a selective alpha-2 adrenoceptor antagonist that blocks presynaptic and postsynaptic alpha-2 adrenergic receptors. By inhibiting alpha-2 adrenoceptor-mediated negative feedback mechanisms, piperoxan increases norepinephrine release in central and peripheral nervous systems. This blockade modulates sympathovagal balance, enhances adrenergic neurotransmission, and influences downstream signaling pathways involved in cardiovascular and neurological regulation. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
54 mg/mL
(200.17 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 54 mg/mL |
| Ethanol | 40 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Piperoxan hydrochloride Solubility in DMSO
- Piperoxan hydrochloride Stock Solution
- Piperoxan hydrochloride Storage
- Piperoxan hydrochloride Stability
- Piperoxan hydrochloride Molecular Weight
- Piperoxan hydrochloride SMILES
- Piperoxan hydrochloride Chemical Structure (2D and 3D)
- Piperoxan hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.