CAS No. 51-03-6
Batch:
Purity:98
Chemical Structure
Check the
Piperonyl butoxide
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 5-[2-(2-butoxyethoxy)ethoxymethyl]-6-propyl-1,3-benzodioxole | |
|---|---|---|
| CAS Number | 51-03-6 | |
| Molecular Formula |
C19H30O5 |
|
| Molecular Weight (MW) | 338.44 | |
| SMILES | CCCCOCCOCCOCC1=CC2=C(C=C1CCC)OCO2 | |
| InChIKey | FIPWRIJSWJWJAI-UHFFFAOYSA-N |
Biological Activity
Piperonyl butoxide is a synthetic pesticide synergist that acts as an inhibitor of cytochrome P450 monooxygenases (P450s). By suppressing cytochrome P450-mediated oxidative metabolism, it prevents the enzymatic detoxification of insecticides within targeted organisms. This metabolic inhibition impairs xenobiotic clearance pathways, thereby dramatically enhancing the biological efficacy and persistence of co-administered insecticidal agents. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
67 mg/mL
(197.96 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.