CAS No. 480-39-7
Batch:
Purity:99.75
Chemical Structure
Check the
Pinocembrin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2S)-5,7-dihydroxy-2-phenyl-2,3-dihydrochromen-4-one | |
|---|---|---|
| CAS Number | 480-39-7 | |
| Molecular Formula |
C15H12O4 |
|
| Molecular Weight (MW) | 256.25 | |
| SMILES | C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=CC=C3 | |
| InChIKey | URFCJEUYXNAHFI-ZDUSSCGKSA-N |
Pinocembrin is a natural flavanone with broad bioactivity, functioning as an antimicrobial, anti-inflammatory, antioxidant, and anticancer agent. It modulates key cellular signaling pathways, including NF-kB and MAPK, reducing pro-inflammatory cytokine expression and attenuating oxidative stress. Furthermore, pinocembrin inhibits cancer cell proliferation and promotes apoptosis through ROS-dependent mitochondrial apoptotic signaling pathways, highlighting its potential across diverse pharmacological research applications.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
51 mg/mL
(199.02 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 51 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.