CAS No. 706782-28-7
Batch:
Purity:99.79
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Chemical Structure
Check the
Pimavanserin tartrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2R,3R)-2,3-dihydroxybutanedioic acid;bis(1-[(4-fluorophenyl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea) | |
|---|---|---|
| CAS Number | 706782-28-7 | |
| Molecular Formula |
C50H68F2N6O4.C4H6O6 |
|
| Molecular Weight (MW) | 1005.2 | |
| SMILES | CC(C)COC1=CC=C(C=C1)CNC(=O)N(CC2=CC=C(C=C2)F)C3CCN(CC3)C.CC(C)COC1=CC=C(C=C1)CNC(=O)N(CC2=CC=C(C=C2)F)C3CCN(CC3)C.C(C(C(=O)O)O)(C(=O)O)O | |
| InChIKey | RGSULKHNAKTFIZ-CEAXSRTFSA-N |
Pimavanserin tartrate is a potent and selective serotonin 5-HT2A receptor inverse agonist. It selectively modulates 5-HT2A receptor-mediated signaling pathways, thereby attenuating hallucinatory behaviors and psychosis-like deficits in animal models without exacerbating motor impairment. These receptor-specific actions downregulate downstream signaling cascades involved in neuropsychiatric dysfunction, supporting its utility in Parkinson's disease-associated psychosis models. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(99.48 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 25 mg/mL |
| DMSO |
100 mg/mL
(99.48 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
| DMSO |
100 mg/mL
(99.48 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 50 mg/mL |
| Ethanol | 3 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Pimavanserin tartrate Clinical Trials
- Pimavanserin tartrate Solubility in DMSO
- Pimavanserin tartrate Stock Solution
- Pimavanserin tartrate Storage
- Pimavanserin tartrate Stability
- Pimavanserin tartrate Molecular Weight
- Pimavanserin tartrate SMILES
- Pimavanserin tartrate Chemical Structure (2D and 3D)
- Pimavanserin tartrate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.