CAS No. 97230-46-1

Batch: Purity:99.72
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Picfeltarraenin IB Chemical Structure
Chemical Structure
Check the Picfeltarraenin IB product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (2R)-2-[(3R,8S,9R,10R,13R,14S,16R,17R)-3-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-16-hydroxy-4,4,9,13,14-pentamethyl-11-oxo-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-5-propan-2-ylfuran-3-one
CAS Number 97230-46-1
Molecular Formula

C42H64O14
Molecular Weight (MW) 792.95
SMILES CC(C)C1=CC(=O)C(CO1)C2C(O)CC3(C)C4CC=C5C(CCC(OC6OC(CO)C(O)C(O)C6OC7OC(C)C(O)C(O)C7O)C5(C)C)C4(C)C(=O)CC23C
InChIKey YRQJYHITIWJZQN-UGBBSPHQSA-N

Ordering Information

Biological Activity

Picfeltarraenin IB is a natural cucurbitacin glycoside isolated from Picria fel-terrae that acts as an inhibitor of acetylcholinesterase (AChE). By suppressing AChE activity, it prevents the breakdown of acetylcholine, thereby promoting cholinergic signaling pathways and modulating downstream cellular responses associated with inflammation and survival. These biochemical mechanisms support its research utility in viral infection, inflammation, and oncology. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
1 mg 5 mg 10 mg
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (126.11 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.