CAS No. 1566-15-0
Chemical Structure
Check the
Phosphoramide mustard cyclohexanamine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 1566-15-0 | |
|---|---|---|
| Molecular Formula |
C6H13N.C4H11Cl2N2O2P |
|
| Molecular Weight (MW) | 320.20 |
Biological Activity
Phosphoramide mustard cyclohexanamine is a DNA alkylating agent and active metabolite of cyclophosphamide that binds guanine residues in DNA to form cytotoxic DNA adducts. These cross-links block replication forks, inducing phosphorylated H2AX (γH2AX) accumulation and activating the ATM-mediated DNA damage response pathway. Furthermore, activation of downstream psignaling promotes cellular senescence and drives cells into apoptosis. [1][2]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Reference
Jump to
- Phosphoramide mustard cyclohexanamine Stock Solution
- Phosphoramide mustard cyclohexanamine Storage
- Phosphoramide mustard cyclohexanamine Stability
- Phosphoramide mustard cyclohexanamine Molecular Weight
- Phosphoramide mustard cyclohexanamine Chemical Structure (2D and 3D)
- Phosphoramide mustard cyclohexanamine SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.