CAS No. 487-39-8
Batch:
Purity:98
Chemical Structure
Check the
Phillygenin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 487-39-8 | |
|---|---|---|
| Molecular Formula |
C21H24O6 |
|
| Molecular Weight (MW) | 372.41 | |
| SMILES | COC1=C(C=C(C=C1)C2C3COC(C3CO2)C4=CC(=C(C=C4)O)OC)OC |
Phillygenin is a natural bioactive lignan exhibiting potent anti-inflammatory, anti-obesity, and antipyretic activities. It modulates key cellular signaling pathways, suppressing NF-kB activation to downregulate downstream pro-inflammatory cytokine expression. Additionally, phillygenin regulates lipid metabolic pathways, leading to reduced blood lipid levels and decreased low-density lipoprotein accumulation, thereby attenuating metabolic dysfunction and associated inflammatory responses. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
74 mg/mL
(198.7 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
74 mg/mL
(198.7 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
74 mg/mL
(198.7 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.