CAS No. 637-03-6
Chemical Structure
Check the
Phenylarsine oxide
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | arsorosobenzene | |
|---|---|---|
| CAS Number | 637-03-6 | |
| Molecular Formula |
C6H5AsO |
|
| Molecular Weight (MW) | 168.03 | |
| InChIKey | BQVCCPGCDUSGOE-UHFFFAOYSA-N |
Biological Activity
Phenylarsine oxide is a membrane-permeable protein tyrosine phosphatase inhibitor that targets vicinal dithiols within active site cysteine residues. By inhibiting protein tyrosine phosphatases, it modulates cellular phosphotyrosine levels and stimulates 2-deoxyglucose transport in skeletal muscle and adipocytes through insulin-independent pathways. Consequently, this compound alters GLUT4 translocation, disrupts endocytosis, and serves as a key tool for investigating insulin signaling mechanisms and metabolic regulation. [1][2]
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Note: Technical data last updated: Sep 1, 2026.