CAS No. 62-44-2

Batch: Purity:100
Phenacetin Chemical Structure
Chemical Structure
Check the Phenacetin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name N-(4-ethoxyphenyl)acetamide
CAS Number 62-44-2
Molecular Formula

C10H13NO2

Molecular Weight (MW) 179.22
SMILES CCOC1=CC=C(C=C1)NC(=O)C
InChIKey CPJSUEIXXCENMM-UHFFFAOYSA-N

Ordering Information

Biological Activity

Phenacetin is a non-opioid analgesic and antipyretic agent devoid of anti-inflammatory properties. It exerts analgesic activity through actions on the sensory tracts of the spinal cord and produces antipyretic effects by acting on the brain to decrease the temperature set point. Additionally, phenacetin exhibits a negative inotropic depressant action on the heart, modulating cardiovascular function and spinal nociceptive processing.

How to Prepare Stock Solution?

Concentration Volume Mass
1 mg 5 mg 10 mg
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 36 mg/mL (200.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 36 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.