CAS No. 67-43-6
Batch:
Purity:98
Chemical Structure
Check the
Pentetic Acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 67-43-6 | |
|---|---|---|
| Molecular Formula |
C14H23N3O10 |
|
| Molecular Weight (MW) | 393.35 | |
| SMILES | C(CN(CC(=O)O)CC(=O)O)N(CCN(CC(=O)O)CC(=O)O)CC(=O)O |
Biological Activity
Pentetic acid is an aminopolycarboxylic acid that functions as a polydentate chelating agent capable of sequestering metal ions. By forming stable coordination complexes with polyvalent cations, pentetic acid prevents metal-induced oxidative damage and inhibits metal-dependent enzyme activities. The resulting depletion of free metal ions alters cellular ion homeostasis and attenuates reactive oxygen species generation driven by transition metals. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| 0.5MNAOH | 3.04 mg/mL |
| DMSO |
0.01 mg/mL
(0.02 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.