CAS No. 591-80-0

Batch: Purity:99.72
4-Pentenoic acid Chemical Structure
Chemical Structure
Check the 4-Pentenoic acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name pent-4-enoic acid
CAS Number 591-80-0
Molecular Formula

C5H8O2

Molecular Weight (MW) 100.12
SMILES C=CCCC(=O)O
InChIKey HVAMZGADVCBITI-UHFFFAOYSA-N

Ordering Information

Biological Activity

4-Pentenoic acid is a fatty acid analog that acts as an inhibitor of mitochondrial fatty acid oxidation. By blocking the β-oxidation pathway in rat heart and liver mitochondria, it impairs acyl-CoA dehydrogenase function and decreases myocardial acetyl-CoA formation. This metabolic inhibition impairs cellular respiration and reduces mitochondrial energy production in cardiac tissue. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.