CAS No. 55916-52-4

Batch: Purity:99.98
Pennogenin 3-O-β-chacotrioside Chemical Structure
Chemical Structure
Check the Pennogenin 3-O-β-chacotrioside product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 55916-52-4
Molecular Formula

C45H72O17

Molecular Weight (MW) 885.04

Ordering Information

Biological Activity

Pennogenin 3-O-β-chacotrioside is an active steroidal saponin isolated from Paris polyphylla that acts as an autophagy modulator. Treatment with this compound increases the expression of key autophagy-related proteins, including LC3 and Beclin-1, thereby inducing autophagic signaling pathways. These cellular alterations contribute to its reported biological activity, demonstrating potent anti-colorectal cancer effects. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (112.98 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.