Molecular Weight: 487.50 g/mol
Chemical Structure
Check the
Pemigatinib (INCB054828)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
40 mg/mL
(82.05 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
40 mg/mL
(82.05 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
| IUPAC Name | 11-(2,6-difluoro-3,5-dimethoxyphenyl)-13-ethyl-4-(morpholin-4-ylmethyl)-5,7,11,13-tetrazatricyclo[7.4.0.02,6]trideca-1,3,6,8-tetraen-12-one | |
|---|---|---|
| CAS Number | 1513857-77-6 | |
| Molecular Formula |
C24H27F2N5O4 |
|
| Molecular Weight (MW) | 487.50 | |
| SMILES | CCN1C2=C3C=C(NC3=NC=C2CN(C1=O)C4=C(C(=CC(=C4F)OC)OC)F)CN5CCOCC5 | |
| InChIKey | HCDMJFOHIXMBOV-UHFFFAOYSA-N |
- Pemigatinib (INCB054828) Mechanism of Action: FGFR2 Inhibition in Cholangiocyte Research
- Pemigatinib (INCB054828) Clinical Trials
- Pemigatinib (INCB054828) Working Concentration | Cell Culture | Treatment
- Pemigatinib (INCB054828) Solubility in DMSO
- Pemigatinib (INCB054828) Stock Solution
- Pemigatinib (INCB054828) Storage
- Pemigatinib (INCB054828) Stability
- Pemigatinib (INCB054828) Combination Database
- Pemigatinib (INCB054828) SMILES
- Pemigatinib (INCB054828) CAS Number
- Pemigatinib (INCB054828) Chemical Structure (2D and 3D)
- Pemigatinib (INCB054828) IC50 for Cell-based and Cell-free Assays
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- Pemigatinib (INCB054828) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.