Molecular Weight: 599.50 g/mol
Chemical Structure
Check the
Pemetrexed (disodium heptahydrate)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 100 mg/mL |
| DMSO |
33 mg/mL
(55.04 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
| IUPAC Name | disodium;(2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate;heptahydrate | |
|---|---|---|
| CAS Number | 357166-29-1 | |
| Molecular Formula |
C20H21N5O6.7H2O.2Na |
|
| Molecular Weight (MW) | 599.50 | |
| InChIKey | QJVSMHJWAOSBMD-MYXYZBIASA-L |
- Pemetrexed (disodium heptahydrate) Solubility in DMSO
- Pemetrexed (disodium heptahydrate) Stock Solution
- Pemetrexed (disodium heptahydrate) Storage
- Pemetrexed (disodium heptahydrate) Stability
- Pemetrexed (disodium heptahydrate) CAS Number
- Pemetrexed (disodium heptahydrate) Chemical Structure (2D and 3D)
- Pemetrexed (disodium heptahydrate) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.