SMILES:
C1=CC2=C(C=C1F)C(=CN2)C=C(C(=O)O)S
Chemical Structure
Check the
PD 151746
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (Z)-3-(5-fluoro-1H-indol-3-yl)-2-sulfanylprop-2-enoic acid | |
|---|---|---|
| CAS Number | 179461-52-0 | |
| Molecular Formula |
C11H8FNO2S
|
|
| Molecular Weight (MW) | 237.25 | |
| SMILES | C1=CC2=C(C=C1F)C(=CN2)C=C(C(=O)O)S | |
| InChIKey | HWMQHECFXSVZGN-KMKOMSMNSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
47 mg/mL
(198.1 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 47 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.