CAS No. 555-57-7
Chemical Structure
Check the
Pargyline
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-benzyl-N-methylprop-2-yn-1-amine | |
|---|---|---|
| CAS Number | 555-57-7 | |
| Molecular Formula |
C11H13N |
|
| Molecular Weight (MW) | 159.23 | |
| InChIKey | DPWPWRLQFGFJFI-UHFFFAOYSA-N |
Pargyline is an irreversible inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1). By targeting LSD1, pargyline blocks chromatin demethylation of histone H3 at lysine 4 (H3K4), resulting in transcriptional repression of androgen receptor target genes. This inhibition disrupts androgen-dependent signaling pathways, suppressing cellular proliferation and demonstrating pharmaceutical potential as an anticancer agent in human prostate cancer models. [1]
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Note: Technical data last updated: Sep 1, 2026.