Panobinostat (LBH589) is a potent pan-HDAC inhibitor. It affects PI3K/AKT and MAPK signaling pathways, by inducing histone hyperacetylation and altering gene expression, to inhibit tumor proliferation and promote apoptosis.
Panobinostat (LBH589) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Panobinostat (LBH589) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.